About Fragility Metrics

The Mission

Improve biomedical research reproducibility by having trials report complete statistical evidence (p-fr-nb triplet) as the standard.

The Framework

The p-fr-nb framework provides a complete assessment of statistical evidence through three orthogonal dimensions:

Developed by Thomas F. Heston, MD, FAAFP at the University of Washington and Washington State University.

Mathematical Foundation

All calculations are model-free, using only published summary statistics. No raw data, simulation, or distributional assumptions required.

Open source implementation available on GitHub for full transparency and reproducibility.

Contact

Thomas F. Heston, MD, FAAFP
ORCID: 0000-0002-5655-2512
DISCUSSION BOARD: GitHub Discussions

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